It’s really hard to pin down because of inconsistencies between manufacturers. I’ve had patients that got pellets and had no effects whatsoever, and some that got way too much because it dissolved too quickly. It also kind of matters who is implanting them and if they know what they’re doing. (Pro tip, chiropractors and naturopaths do not know what the fuck they are doing.)

The problem with pellets is that they can release the hormones at uneven rates as they dissolve because they aren’t perfectly homogeneous. There’s also a chance that your body rejects it and forms a fibrous capsule around it that prevents it from releasing the hormones at all.

That was after she charged at the guy with the intent to punch him. Dude was tackled by security for his own safety.

They were brutalizing the protesters at the Whipple federal building and the airport where they arrested 100 clergy that were blocking the entrance and singing hymns.

*But the study was really poorly designed and every single CI crossed 1.0

That is indeed the gun going off. It looks like there’s a flash suppressor on there, but higher-resolution versions of the clip show the gas blow back from the bullet firing.

No, that was a negligent discharge. They are actually walking around with their fingers on the trigger and the safety off.

Well, I’ll just take this as an excuse to get food from some of my favorite places in St Paul.

Yeah, I have him on Patreon, but I want to see the whole thing when it’s done. He had a couple side videos on Patreon about Oreos that nearly amounted to a cookie crash out that were very amusing last year.

Look, the man is making feature-length films about rabbit holes he never expected to find. The “Roblox OOF!” video was supposed to be about 10-20 minutes, but then he found the Tommy Tallarico absurdity and just couldn’t leave that part out.

IRL? H. Bomberguy

In fiction? Deadpool.

Honestly, a lot of bisexual and pansexual men and masculine characters are pretty well adjusted in part due to the fact that they are comfortable with who they are as a person and know what kinds of things make men attractive. Way too many men these days have a completely warped idea of what other people find attractive in men and toxic masculinity is built on a framework of those misconceptions.

No, it’d be the Orange Cube.

But occasional use for moderate pain is quite reasonable and people should not be afraid to take medications at the doses and frequency listed in the instructions. For those with liver or kidney problems, listen to your doctor about what medications to avoid and what to use in their place, but don’t suffer unnecessarily.

Taking these meds once in a while is perfectly safe if you don’t have preexisting organ damage or dysfunction.

It’s quite hard to actually overload your liver with the artificial sweeteners unless you are drinking literal gallons of zero sugar pop a day or eating nothing besides artificially sweetened foods. The stuff is used in such tiny concentrations that someone would have to deliberately seek out overdosing on this stuff to get the same effects as the experimental animals are getting (because the experimental animals are being fed pure sorbitol in doses that no human could reasonably consume.)

That’s the problem with articles like this is that they don’t emphasize that they are only seeing this in animal models and they don’t disclose just how much of the stuff they had to give to the animal for the negative effects to occur. It’s also a bad study because it doesn’t account for the differences in the physiology and biochemistry between humans and zebrafish, nor does it account for the confounding factors in humans. You know who drinks and eats a lot of artificially sweetened things? People with diabetes and people who are trying to lose weight. These are people that are likely to already have fatty liver disease and the sorbitol didn’t really have much to do with it.

Copied from another posting of this article:

The headline (and the article for that matter) are very sensationalist and I don’t think they’ve presented this in a balanced way. They are discussing how sorbitol behaves in zebrafish with limited data presented on human biochemistry, and they discuss it in a vacuum without quantifying the amount of sorbitol it takes to cause a problem. Yes, any substance in excess can be harmful, but the amount of sorbitol in food compared to the amount of high fructose corn syrup makes it the substantially lesser evil. The artificial sweeteners are vastly more potent than actual sugar, so you don’t need very much of it to get the same amount of sweetness. High fructose corn syrup is used in massive amounts in food and is much worse for you on the scale that either substance would be consumed.

The headline (and the article for that matter) are very sensationalist and I don’t think they’ve presented this in a balanced way. They are discussing how sorbitol behaves in zebrafish with limited data presented on human biochemistry, and they discuss it in a vacuum without quantifying the amount of sorbitol it takes to cause a problem. Yes, any substance in excess can be harmful, but the amount of sorbitol in food compared to the amount of high fructose corn syrup makes it the substantially lesser evil. The artificial sweeteners are vastly more potent than actual sugar, so you don’t need very much of it to get the same amount of sweetness. High fructose corn syrup is used in massive amounts in food and is much worse for you on the scale that either substance would be consumed.

What on earth do you have against paragraphs? I don’t want to read your comments just based on the formatting, let alone the actual content.

Responding to the content though: In this situation, this woman was being social at a bar with her friends. Women existing in public is not an open invitation to bother them and being unable to read social cues is probably a big part of Anon’s problems with women. Women utilize a great deal of non-verbal communication and not being able to read that or refusing to even try is a great way to plaster oneself in red flags.

I don’t think this will be a conversation you will be able to have with him, but it’s probably something you need to have for yourself for your own sanity. There is the adage that “your mental health is not your fault, but it is your responsibility”, that I think is very applicable here. I know that the manifestations of his mental illness at this time are damaging your quality of life, but I think that you are suffering additional, semi-self-inflicted harm by internalizing any amount of responsibility for his behavior. It is a bit like intentional cognitive dissonance, but I think you would benefit from divorcing yourself of any sense of responsibility for fixing this situation.

There are some good suggestions in this thread about strategies for set cleaning times with reference images of what each room is supposed to look like, and to some extent, mild parenting techniques to get some sense of order in the house. If I were in your shoes, this is the list of things I would try to implement:

• Set deadlines for cleaning tasks

    - ("dishes must be done by PERSON by end of DAY" or "living room must be clean of personal items by 10PM every night)
  

• Make a list or a calendar on a whiteboard in the kitchen

    - (columns for days of the week with check boxes for needed tasks and written communications instead of verbal)
  

• Clear delineation of responsibilities

     - ("you make the mess, you clean it up" or "wash/put dishes in the dishwasher immediately when done using them or before bed that night")
  

(The strategy for dishes can be variable, I just feel like dishes are a good example for figuring out household responsibilities.)

Also, make it clear that his actions are harming you. It may feel dramatic, but it’s true. And I think a way around the bluescreen issue is to write a letter explaining your needs and how his actions are affecting you. I would recommend hand-writing this because it will appear more personal, and be less easily dismissed. Putting it in writing makes it so that he has a physical object to refer to when his mind tries to edit out the uncomfortable thing. But still give him the letter in a conversation. I would start it with saying:

“Hey ____, I’ve tried to talk to you about this before, but I don’t think I’ve been communicating with you in a way that works. There’s some things going on in the house with your cleaning habits and behaviors that are really messing with me and it’s putting me in a bad place mentally to have the common areas this messy all the time. I know these conversations can be really overwhelming for you, so I wrote this letter for you to read when you’re ready. Please come talk to me after you’ve read it so we can work out some strategies to make living together more comfortable for everyone.”

This is my advice from having had difficult roommates and friends that don’t deal with their mental health, and from the perspective of a medical professional. I’m a medical student, but I’ve done a lot of work with mental health and substance use disorder patients and I always try to work with folks to find strategies that work for them to improve their quality of life. I see medications as an adjunct to building accommodations for oneself, but I always emphasize that the medications are exactly the same as medications for things like high blood pressure. For some folks, there’s a physiologic dysfunction that you can’t “life strategy” your way out of, and you just need to get the chemicals in your brain to behave properly so you can function.

(This ended up longer than intended, sorry for the essay)

Normally I would agree with you, but OP is living in the environment created by the roommate’s symptoms. This is obviously uncontrolled or, at best, extremely poorly managed mental illness and it is not reasonable to expect OP (who is this person’s roommate, not explicitly a friend, certainly not a family member, and definitely not a partner) to sacrifice their own wellbeing in deference to this person’s dysfunction.

OP obviously has empathy for this person, but is clearly at the end of their rope, and your pontificating and language policing from the outside doesn’t actually help OP or the roommate in any way. I work in medicine, I deal with a LOT of mental health patients, and your comment here doesn’t read as any kind of advocacy for people suffering from mental illnesses, it just reads as virtue signalling or sanctimonious tone policing.

They once tried to prove that DNPs (Doctorate of Nurse Practitioner) was just as good as an MD or DO education. They did this by taking the top DNP grads from the best programs and gave them a dumbed down version of the easiest part of the medical license exam, and only 40% passed it.

For context, to get a medical license, a physician has to have passed Steps 1-3 of the USMLE (US Medical License Exam) or Levels 1-3 of COMLEX (Comprehensive Osteopathic Medical Licensing Exam) to be eligible to apply for a medical license. Step/Level 2 is usually considered the hardest one of the three, and Step/Level 3 is the longest exam (2 full days), but generally considered to be the easiest. This DNP exam took the easiest 20% of questions from Step 3 and made a half-length version of the exam…and 60% of the DNPs still failed it.

The NP/DNP education is almost entirely algorithm-based and doesn’t meaningfully get into the anatomy, physiology, pathophysiology, and pharmacology that the first 2 years of medical school are devoted to. I have seen NPs miss life-threatening diagnoses because they were rare diseases that don’t come up outside of those first 2 years of drinking from a firehose of textbooks in medical school. Their education just isn’t long enough or in-depth enough to actually be equivalent to an MD or DO degree.

Also, MDs and DOs have almost 4000 hours of supervised medical practice where a physician is checking their work and directly observing or guiding their clinical experience before finishing medical school. Residency is, at minimum, another 8000 to 10000 hours of supervised practice in the specialties that only require 3 years of residency (it ranges from 3 to 9 years based on specialty).

NPs don’t have any standardized requirements for supervised practice to get their licenses and most programs only require 1000 hours or less of shadowing where they are just observing a licensed NP practice and not actually doing anything hands-on themselves… And they try to argue that this education is sufficient for them to be equal to physicians. There are some NPs who are amazing providers, but they’re usually the ones that were bedside nurses for 10+ years before going back to school for their NP license. The newer NPs that are going straight through from their BSN without any actual experience are the really dangerous ones.

TO BE CLEAR: I love the nurses I work with and I value their work and their input immensely. I was an EMT/ER tech before med school and it’s really sad when nurses are so confused when I help them clean up patients or reposition or whatever as a med student because most physicians and medical students don’t stop to help the nurses clean up poop. You can always tell which physicians have never had to clean up poop before, and I try very hard not to be like them.